According to a survey conducted by Cheaphotels.org, Boston is the most expensive city in the U.S. based on cost of lodging. The survey compared 50 destinations based on their hotel rates during October 2021.

October was chosen as it's the month when most U.S. cities reach their highest average rates. It has to be noted further that only centrally located hotels with a 3-star rating or higher were considered for the survey.

Boston leads the rankings at an average price of $236 for the most affordable double room. Nashville and Albuquerque complete the podium with rates of $209 and $184, respectively. Las Vegas is the least expensive destination, averaging just $52 per night.

On average, hotel rates are still about 20% more affordable than they were in 2019 across the 50 destinations considered by the survey. In certain cities, they are down even more: Houston (-35%); New York City (-42%); and San Francisco (-46%). In Boston and a few other destinations—such as Sacramento and Cleveland—however, rates are more expensive now compared to pre-Covid levels.

The following table compares 50 city destinations in the United States. Prices shown reflect the average rate for each city's cheapest available double room (minimum 3-star hotel) in the city center for the period between October 1–31, 2021.

1. Boston	$236	26. Miami	$125
2. Nashville	$209	27. Indianapolis	$124
3. Albuquerque	$184	28. Dallas	$124
4. Sacramento	$182	29. Memphis	$124
5. Cleveland	$178	30. New Orleans	$123
6. Denver	$176	31. Chicago	$124
7. Austin	$174	32. Baltimore	$120
8. Cincinnati	$165	33. Tulsa	$117
9. Pittsburgh	$150	34. Oklahoma City	$115
10. Fort Worth	$148	35. Mesa	$114
11. El Paso	$147	35. Philadelphia	$114
12. Kansas City	$145	37. San Diego	$114
13. Charlotte	$144	38. San Francisco	$112
14. Orlando	$144	39. Atlanta	$112
15. Portland	$135	40. New York City	$112
16. Washington DC	$135	41. Houston	$110
17. Jacksonville	$134	42. Tucson	$109
18. Milwaukee	$134	43. Omaha	$109
19. Los Angeles	$134	44. San Antonio	$108
20. Columbus	$134	45. Louisville	$107
21. Raleigh	$132	46. St. Louis	$104
22. Seattle	$132	47. Honolulu	$95
23. San Jose	$130	48. Minneapolis	$91
24. Phoenix	$127	49. Fresno	$85
25. Detroit	$125	50. Las Vegas	$52